Table 7.
Pairwise comparison results from network meta-analysis on all-cause death.
| Albiglutide | 0.9 (0.72–1.13) | 0.98 (0.78–1.23) | 0.95 (0.76–1.19) | 0.72 (0.55–0.93) | 0.98 (0.77–1.25) | 0.91 (0.72–1.13) | 0.89 (0.71–1.13) | 0.99 (0.76–1.29) | 0.54 (0.32–0.91) | 1.05 (0.87–1.28) | 1 (0.78–1.28) | 1.11 (0.74–1.65) |
| 1.11 (0.89–1.4) | Canagliflozin | 1.09 (0.92–1.29) | 1.05 (0.89–1.25) | 0.79 (0.64–0.99) | 1.09 (0.9–1.32) | 1.01 (0.85–1.19) | 0.99 (0.83–1.19) | 1.1 (0.88–1.37) | 0.6 (0.36–0.99) | 1.17 (1.03–1.32) | 1.11 (0.91–1.36) | 1.23 (0.85–1.79) |
| 1.02 (0.81–1.28) | 0.92 (0.77–1.09) | Dapagliflozin | 0.97 (0.82–1.14) | 0.73 (0.59–0.91) | 1 (0.83–1.21) | 0.92 (0.78–1.09) | 0.91 (0.76–1.09) | 1.01 (0.81–1.26) | 0.55 (0.33–0.91) | 1.08 (0.95–1.21) | 1.02 (0.84–1.24) | 1.13 (0.78–1.64) |
| 1.05 (0.84–1.32) | 0.95 (0.8–1.12) | 1.03 (0.87–1.22) | Dulaglutide | 0.75 (0.61–0.94) | 1.03 (0.86–1.25) | 0.96 (0.81–1.13) | 0.94 (0.79–1.13) | 1.04 (0.84–1.3) | 0.57 (0.34–0.94) | 1.11 (0.99–1.25) | 1.05 (0.87–1.28) | 1.17 (0.81–1.7) |
| 1.4 (1.07–1.82) | 1.26 (1.01–1.57) | 1.37 (1.1–1.7) | 1.32 (1.07–1.64) | Empagliflozin | 1.37 (1.08–1.73) | 1.27 (1.02–1.57) | 1.25 (0.99–1.57) | 1.38 (1.07–1.79) | 0.75 (0.44–1.27) | 1.47 (1.23–1.76) | 1.4 (1.1–1.78) | 1.55 (1.04–2.3) |
| 1.02 (0.8–1.3) | 0.92 (0.76–1.12) | 1 (0.83–1.21) | 0.97 (0.8–1.17) | 0.73 (0.58–0.92) | Ertugliflozin | 0.92 (0.76–1.12) | 0.91 (0.75–1.12) | 1.01 (0.8–1.28) | 0.55 (0.33–0.92) | 1.07 (0.93–1.25) | 1.02 (0.82–1.27) | 1.13 (0.77–1.65) |
| 1.1 (0.88–1.38) | 0.99 (0.84–1.18) | 1.08 (0.92–1.28) | 1.05 (0.89–1.23) | 0.79 (0.64–0.98) | 1.08 (0.9–1.31) | Exenatide | 0.99 (0.83–1.18) | 1.09 (0.88–1.36) | 0.59 (0.36–0.98) | 1.16 (1.04–1.3) | 1.1 (0.91–1.34) | 1.22 (0.84–1.77) |
| 1.12 (0.88–1.41) | 1.01 (0.84–1.21) | 1.09 (0.92–1.31) | 1.06 (0.89–1.27) | 0.8 (0.64–1.01) | 1.09 (0.89–1.34) | 1.01 (0.85–1.21) | Liraglutide | 1.11 (0.88–1.39) | 0.6 (0.36–1) | 1.18 (1.03–1.35) | 1.12 (0.91–1.37) | 1.24 (0.85–1.81) |
| 1.01 (0.78–1.32) | 0.91 (0.73–1.14) | 0.99 (0.79–1.23) | 0.96 (0.77–1.19) | 0.72 (0.56–0.94) | 0.99 (0.78–1.25) | 0.91 (0.74–1.14) | 0.9 (0.72–1.14) | Lixisenatide | 0.54 (0.32–0.92) | 1.06 (0.88–1.28) | 1.01 (0.79–1.29) | 1.12 (0.75–1.66) |
| 1.86 (1.1–3.17) | 1.68 (1.01–2.79) | 1.82 (1.1–3.03) | 1.76 (1.06–2.94) | 1.33 (0.79–2.26) | 1.82 (1.09–3.06) | 1.68 (1.02–2.8) | 1.66 (1–2.79) | 1.84 (1.09–3.13) | Osemaglutide | 1.96 (1.19–3.21) | 1.86 (1.11–3.12) | 2.06 (1.13–3.76) |
| 0.95 (0.78–1.15) | 0.85 (0.76–0.97) | 0.93 (0.83–1.05) | 0.9 (0.8–1.01) | 0.68 (0.57–0.82) | 0.93 (0.8–1.08) | 0.86 (0.77–0.96) | 0.85 (0.74–0.97) | 0.94 (0.78–1.13) | 0.51 (0.31–0.84) | Placebo | 0.95 (0.81–1.11) | 1.05 (0.74–1.5) |
| 1 (0.78–1.28) | 0.9 (0.74–1.1) | 0.98 (0.8–1.19) | 0.95 (0.78–1.15) | 0.72 (0.56–0.91) | 0.98 (0.79–1.21) | 0.91 (0.75–1.1) | 0.89 (0.73–1.1) | 0.99 (0.78–1.26) | 0.54 (0.32–0.9) | 1.05 (0.9–1.23) | Sotagliflozin | 1.11 (0.75–1.63) |
| 0.9 (0.6–1.35) | 0.81 (0.56–1.18) | 0.88 (0.61–1.28) | 0.86 (0.59–1.24) | 0.65 (0.43–0.96) | 0.89 (0.6–1.3) | 0.82 (0.56–1.18) | 0.81 (0.55–1.18) | 0.89 (0.6–1.33) | 0.49 (0.27–0.89) | 0.95 (0.67–1.35) | 0.9 (0.61–1.33) | Ssemaglutide |