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. 2021 Jul 16;15:692304. doi: 10.3389/fnhum.2021.692304

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Copyright © 2021 Hu, Cheng, Ji, Chong, Lu, Huang, Ang, Phua, Chuang, Jiang, Chew, Guan and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ALFF changes in contralesional SMN and posterior DMN in stroke patients along with motor function recovery. (A) The interaction between time and group. The MI-BCI group and MI-BCI + tDCS group showed divergent intervention effects at contralesional SMN and DMN. (B) Intervention effect in MI-BCI group. MI-BCI group showed increased ALFF at contralesional SMN and decreased ALFF at DMN. No such effect was observed in the MI-BCI + tDCS group. (C) Correlation between FMA changes and ALFF changes in the MI-BCI group. A positive correlation was observed between FMA changes and ALFF changes post intervention in the MI-BCI group at the precentral gyrus. No such correlation was observed in the MI-BCI + tDCS group. L, Ipsilesional Hemisphere; DMN, Default Mode Network; SMN, Somatomotor Network: HC, Healthy Control; Precg, Precentral Gyrus; SMA, Supplementary Motor Area; PCUN, Precuneus; PCG, Posterior Cingulate Gyrus; MFG, Middle Frontal Gyrus; ANG, Angular Gyrus; INS, Insula; MTG, Middle Temporal Gyrus.