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. 2021 Jul 16;12:709607. doi: 10.3389/fphar.2021.709607

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Copyright © 2021 Zhang, Zhao, Wang, Guo, Liu and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Various constituents suppressed SNP-induced cytotoxicity in SH-SY5Y cells. Cells were pre-treated with different concentrations of Dihydrocapsaicin (A), Rhapontigenin (B), 6-Shogaol (C), 10-Gingerol (D), Nonivamide (E), Carnosol (F), Bavachromene (G) or 0.1% DMSO for 2 h and then incubated with or without SNP (600 μM) for 24 h and the cell viability was detected by MTT assay. Results are shown as the mean ± SEM and represent three independent experiments. ###p < 0.001 compared with control group, *p < 0.05, **p < 0.01, ***p < 0.001 compared with SNP treated group.