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. 2021 Jul 16;9:658115. doi: 10.3389/fcell.2021.658115

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Copyright © 2021 Yu, Lin, Ai, Tan, Huang and Zou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circ_PVT1 regulated LC cells progression via targeting miR-21-5p/CBX4 signal pathway. (A) The level of CBX4 was detected by qRT-PCR. *P < 0.05 vs. Control, ^#P < 0.05 vs. miR-21-5p. n = 4. (B) The CCK-8 assay was performed in Hep-2 cells. *P < 0.05 vs. Control, ^#P < 0.05 vs. miR-21-5p. n = 4. (C) The clone formation assay was performed in Hep-2 cells. *P < 0.05 vs. Control, ^#P < 0.05 vs. miR-21-5p. n = 4. (D) Wound healing assay was performed in Hep-2 cells. *P < 0.05 vs. Control, ^#P < 0.05 vs. miR-21-5p. n = 4. (E,F) Transwell migration and invasion assay was performed in Hep-2 cells. *P < 0.05 vs. Control, ^#P < 0.05 vs. miR-21-5p. n = 4.