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Epitope spreading in mouse models after autoantigen immunization.
| Antigen | Autoimmune Epitope Spread | Reference |
|---|---|---|
| Ro 60 (aa 316–335) | Ro60, La, Sm, U1RNP | (176) |
| SmD1 protein | A-RNP, SmD | (176) |
| SmB protein | A-RNP, SmD | (176) |
| SmD183–119 | SmD, dsDNA | (177) |
| SmB′/B aa PPPGMRPP | SmD, 70k-/A-U1RNP | (178) |
| Murine La (aa 13–30) | Ro52 | (179) |
| A2/B1 hnRNP (aa 50–70) | hnRNP | (180) |
| Nucleosome (lupus-prone mice) | dsDNA, nucleosome, histone | (181) |
| La (aa 13–30) | La, Ro | (179) |
| Histone H1 | H2, ssDNA | (182) |
