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. 2021 Jul 16;8:703307. doi: 10.3389/fmolb.2021.703307

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Copyright © 2021 Chen, Wu, Yi, Feng, Chang, Chen, Gao, Chen and Zhen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of robust DEGs in the RRA analysis. (A) The lollipop chart showed the top 20 ranked genes identified by the RRA method. The red and blue dots represented the up- and down-regulated genes, respectively. Bigger dots represented higher ranks; (B) The heatmap showed the top 10 up- and down-regulated DEGs in five GEO series. Red represented high expression of DEGs in asthma patients, while blue represented low expression of DEGs in asthma patients. The numbers in the box indicated logarithmic fold changes in each dataset; (C) The circular heatmaps showed the chromosomal positions of all robust DEGs. The outer circle represented chromosomes, while the inner circle heatmaps represented logarithmic fold changes of all robust DEGs in five asthma microarray datasets.