Table 2.
Univariable Mixed Linear Effects Models of Determinants of Peripapillary Vessel Density (pVD) in Non-Glaucoma and Subjects With Glaucoma
| Non-Glaucoma | Glaucoma | |||||
|---|---|---|---|---|---|---|
| Variable | β | CI | P Value | β | CI | P Value |
| Age (years) | −0.00165 | (−0.00189 to −0.00140) | <0.001 | −0.00065 | (−0.00240 to 0.00111) | 0.472 |
| IOP (mm Hg) | −0.00086 | (−0.00170 to −0.00002) | 0.045 | −0.00458 | (−0.00694 to −0.00221) | <0.001 |
| AL (mm) | −0.01334 | (−0.01589 to −0.01079) | <0.001 | −0.02820 | (−0.04242 to −0.01398) | <0.001 |
| RNFL (micron) | 0.00254 | (0.00237 to 0.00271) | <0.001 | 0.00356 | (0.00294 to 0.00418) | <0.001 |
| SS | 0.02416 | (0.02227 to 0.02605) | <0.001 | 0.03202 | (0.01920 to 0.04483) | <0.001 |
Beta-estimate, CI, and P value generated from mixed linear effects model controlling for inter-eye correlation. Significance level was 0.05. CI = confidence interval; IOP = intraocular pressure; AL = axial length; RNFL = retinal nerve fiber layer thickness; pVD = peripapillary vessel density; SS = signal strength (on a scale of 1–10).