Table 4.
Multivariable Mixed Linear Regression of Determinants of Peripapillary Vessel Density (pVD) of Short and Long Axial Length in Non-Glaucomatous and Glaucomatous Eyes
| Non-Glaucoma Short AL | Non-Glaucoma Long AL | |||||
|---|---|---|---|---|---|---|
| Variable | β | CI | P Value | β | CI | P Value |
| Age (years) | −0.00073 | (−0.00096 to −0.00051) | <0.001 | −0.00088 | (−0.00110 to −0.00066) | <0.001 |
| IOP (mm Hg) | −0.00040 | (−0.00109 to 0.00029) | 0.257 | −0.00023 | (−0.00092 to 0.00047) | 0.526 |
| RNFL (micron) | 0.00216 | (0.00197 to 0.00234) | <0.001 | 0.00225 | (0.00205 to 0.00245) | <0.001 |
| SS | 0.02209 | (0.01969 to 0.02448) | <0.001 | 0.02014 | (0.01804 to 0.02223) | <0.001 |
| Glaucoma Short AL | Glaucoma Long AL | |||||
| Variable | β | CI | P Value | β | CI | P Value |
| Age (years) | −0.00028 | (−0.00179 to 0.00124) | 0.723 | −0.00123 | (−0.00214 to −0.00033) | 0.011 |
| IOP (mm Hg) | −0.00075 | (−0.00269 to 0.00119) | 0.445 | −0.00235 | (−0.00391 to −0.00079) | 0.005 |
| RNFL (micron) | 0.00249 | (0.00181 to 0.00318) | <0.001 | 0.00372 | (0.00305 to 0.00439) | <0.001 |
| SS | 0.02998 | (0.01550 to 0.04446) | <0.001 | 0.02146 | (0.01273 to 0.03020) | <0.001 |
Beta-estimate, CI, and P value generated from mixed linear effects model controlling for inter-eye correlation. Significance level was 0.05. IOP = intraocular pressure; RNFL = retinal nerve fiber layer thickness; SS = signal strength. Longer axial length was defined as ≥ 23.46 mm, the median for the study population.