Table 1.
Selected demographic and clinical characteristics.
| Clinical characteristicsa | Normal (n = 51) | CAD (n = 205) | p-valueb |
|---|---|---|---|
| Demography | |||
| Age (years), μ ± σ | 58.4 ± 7.35 | 63.4 ± 7.93 | ≪0.001 |
| Female sex | 72.5% | 28.8% | ≪0.001 |
| Clinical factors | |||
| BMI | 27.3 ± 3.53 [49] | 27.6 ± 3.80 [202] | 0.64 |
| Current smoker | 9.8% | 17.6% | 0.255 |
| Hypertension | 52.9% | 70.7% | 0.024 |
| Diabetes | 9.8% | 24.9% | 0.032 |
| Dyslipidemia | 84.3% | 86.3% [204] | 0.893 |
| Family history of CAD | 49.0% | 43.4% | 0.573 |
| Clinical symptoms | |||
| Typical chest pain | 35.3% | 18.0% | 0.003 |
| Atypical chest pain | 49.0% | 44.9% | |
| Non-anginal chest pain | 15.7% | 37.1% | |
| Biomolecular characterization | |||
| Triglycerides (mg/dl), μ0.5 (IQR) | 89 (70–124) | 112.5 (81–158.3) [204] | 0.007 |
| Total cholesterol (mg/dl), μ0.5 (IQR) | 199 (161–231) | 181 (146–212) | 0.045 |
| HDL-C (mg/dl), μ0.5 (IQR) | 56.0 (47.5–62.5) | 50.0 (41–59) [204] | 0.016 |
| Hs-cTnT (ng/L), μ0.5 (IQR) | 3.59 (3.00–4.96)[45] | 6.99 (4.43–9.32) [180] | ≪0.001 |
| Therapies | |||
| Statins | 39.2% | 55.6% | 0.052 |
| ACE inhibitors/ARBs | 31.4% | 54.1% | 0.006 |
| Diuretics | 11.8% | 19.0% | 0.31 |
| β-blockers | 47.1% | 43.9% | 0.80 |
| Aspirin | 49.0% | 64.4% | 0.063 |
Summaries are derived on available data and do not account for imputations.
For categorical variables, data are presented as percentages. Pearson's chi-square test or Fisher's exact test was used for comparisons. For continuous variables, either the mean and standard deviation, μ ± σ, or the median and interquartile range expressed as an interval, μ0.5 (IQR), is specified from time to time, according to either normality or non-normality graphical indications. The test is either the two-sided t-test or the Mann–Whitney test, respectively. The number of subjects with available data is reported in square brackets if different from the total number in the group (normal and CAD).
p ≪ 0.001 means order of magnitude <-4.