Table 2.
Considered ceramides, triglycerides, and sphingomyelins.
| Lipid species |
Normal (μmol/L)a (n = 51) |
CAD (μmol/L)a (n = 205) |
p-valueb |
|---|---|---|---|
| Cer(d18:1/16:0) | 0.52 (0.31–0.75) | 0.43 (0.29–0.62) | 0.067 |
| Cer(d18:1/18:0) | 0.09 (0.06–0.11) [46] | 0.09 (0.06–0.14) [181] | 0.61 |
| TG(50:1) | 185.5 (108.5–235.5) | 198.2 (144.4–269.9) | 0.12 |
| TG(50:2) | 66.1 (42.8–109.9) | 81.7 (55.9–116.5) | 0.09 |
| TG(52:2) | 182.6 (158.5–219.1) | 205.8 (175.5–853.7) | 0.008 |
| TG(52:3) | 74.1 (62.0–99.4) | 92.8 (73.0–112.4) | 0.004 |
| TG(54:2) | 50.8 (31.5–63.4) | 56.2 (40.3–85.32) | 0.027 |
| TG(54:3) | 72.1 (51.8–86.6) | 82.2 (59.7–99.0) | 0.016 |
| SM(34:1) | 139.7 (131.6–151.4) [46] | 134.3 (121.8–143.7) [180] | 0.013 |
| SM(36:2) | 24.4 (19.9–27.7) | 20.9 (17.6–24.7) | 0.002 |
| SM(38:2) | 14.0 (12.1–16.2) | 12.4 (10.3–14.7) | 0.001 |
| SM(38:1) | 49.0 (42.6–54.99) | 44.6 (37.6–54.0) | 0.078 |
| SM(40:3) | 7.3 (6.4–9.2) [50] | 6.6 (5.3–9.0) [191] | 0.046 |
| SM(40:2) | 69.4 (61.8–81.2) | 61.2 (52.2–73.2) | 0.002 |
| SM(40:1) | 114.9 (94.2–124.6) [48] | 107.1 (92.5–122.5) [195] | 0.19 |
| SM(41:2) | 49.9 (40.7–60.3) | 41.8 (33.8–52.3) | 0.003 |
| SM(41:1) | 58.9 (49.3–72.2) | 52.0 (42.4–68.4) | 0.035 |
| SM(42:4) | 7.6 (6.4–10.1) | 6.8 (5.6–9.2) | 0.030 |
| SM(42:3) | 99.9 (89.7–115.2) [50] | 94.7 (77.9–109.1) [204] | 0.024 |
| SM(42:1) | 87.7 (67.0–100.0) | 79.0 (65.3–97.5) [203] | 0.15 |
Summaries are derived on available data and do not account for imputations.
a
Median and interquartile range expressed as an interval, μ0.5 (IQR).
b
The test is the two-sided Mann–Whitney test. The number of subjects with available data is reported in square brackets if different from the total number in any of the two groups (normal and CAD).