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. 2021 Jul 16;12:696680. doi: 10.3389/fmicb.2021.696680

FIGURE 4.

FIGURE 4

Assessment of the level of cytokines in the plasma of AHE patients. (A–F) The level of cytokines, including IFN-Ɣ (A), IL-1β (B), IL-12 (C), IL-2 (D), IL4 (E), and IL-10 (F), was measured in the plasma of healthy controls (n = 8), plasma of AHE patients who tested positive for the (+) RNA strand in the PBMCs (n = 10), and plasma of AHE patients who tested positive for (+) and (–) RNA strands in the PBMCs (n = 4). Data represented as mean ± SEM. * (gray); compare AHE vs. healthy control, * (brown): compare AHE patients with detectable (+) and (–) RNA strands in the PBMCs vs. AHE patients with detectable (+) RNA strand in the PBMCs. *, **, ***, and **** means p < 0.05, 0.01, 0.001, and 0.0001, respectively, as determined by one-way ANOVA multiple comparison test.