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Diploid genotype-to-phenotype prediction
(A) Formal representations of the three tested models with an example variant.
(B) The model predictions for all early-onset, late-onset, and random reference cohorts as they change with increasing model complexity.
(C and D) Precision-recall curve of all models, evaluated on early-onset cases versus random reference individuals (C) and early-onset versus late-onset individuals (D).
