TABLE 1.
Alteration frequency of MUC4 across different cancer types in cBioPortal.
| Cancer type | Cancer type details | Multiple alterations | Amplification | Deep deletion | Mutation | Fusion | Total |
| (%) | (%) | (%) | (%) | (%) | (%) | ||
| LUSC | Lung squamous cell carcinoma | 2.053 | 27.721 | 3.901 | 33.676 | ||
| ESAC | Esophageal adenocarcinoma | 1.099 | 17.582 | 8.242 | 26.923 | ||
| CESC | Cervical squamous cell carcinoma | 4.377 | 9.764 | 12.458 | 26.599 | ||
| UCEC | Uterine corpus endometrial carcinoma | 0.756 | 6.049 | 16.257 | 23.062 | ||
| SKCM | Skin cutaneous melanoma | 0.225 | 0.225 | 0.225 | 17.117 | 17.793 | |
| OV | Ovarian serous cystadenocarcinoma | 0.342 | 15.582 | 0.514 | 1.027 | 17.466 | |
| HNSC | Head and neck squamous cell carcinoma | 0.765 | 12.237 | 1.912 | 14.914 | ||
| STAD | Stomach adenocarcinoma | 0.455 | 4.091 | 0.455 | 5.455 | 10.455 | |
| UCS | Uterine carcinosarcoma | 7.018 | 1.754 | 8.772 | |||
| BLCA | Bladder urothelial carcinoma | 3.406 | 0.243 | 5.109 | 8.759 | ||
| COAD | Colorectal adenocarcinoma | 0.168 | 6.902 | 7.071 | |||
| ACC | Adrenocortical carcinoma | 6.593 | 6.593 | ||||
| DLBC | Diffuse large B-cell lymphoma | 4.167 | 2.083 | 6.250 | |||
| BRCA | Breast invasive carcinoma | 0.554 | 1.753 | 0.092 | 3.690 | 6.089 | |
| LUAD | Lung adenocarcinoma | 0.353 | 1.590 | 1.237 | 2.650 | 5.830 | |
| LIHC | Liver hepatocellular carcinoma | 1.075 | 3.763 | 4.839 | |||
| SARC | Sarcoma | 0.784 | 0.784 | 2.353 | 3.922 | ||
| PRAD | Prostate adenocarcinoma | 1.215 | 2.024 | 0.607 | 3.846 | ||
| PAAD | Pancreatic adenocarcinoma | 0.543 | 1.630 | 0.543 | 0.543 | 3.261 | |
| CHOL | Cholangiocarcinoma | 2.778 | 2.778 | ||||
| LGG | Brain lower-grade glioma | 0.584 | 1.362 | 0.778 | 2.724 | ||
| UVM | Uveal melanoma | 2.500 | 2.500 | ||||
| KIRP | Kidney renal papillary cell carcinoma | 0.707 | 1.767 | 2.473 | |||
| MESO | Mesothelioma | 2.299 | 2.299 | ||||
| GBM | Glioblastoma multiforme | 0.845 | 1.351 | 2.196 | |||
| KIRC | Kidney renal clear cell carcinoma | 0.391 | 0.978 | 0.783 | 2.153 | ||
| THYM | Thymoma | 0.813 | 0.813 | 1.626 | |||
| AML | Acute myeloid leukemia | 0.500 | 1.000 | 1.500 | |||
| TGCT | Testicular germ cell tumors | 0.671 | 0.671 | ||||
| THCA | Thyroid carcinoma | 0.200 | 0.200 | ||||
| KICH | Kidney chromophobe | ||||||
| PCPG | Pheochromocytoma and paraganglioma |