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. 2021 Jul 16;11:661184. doi: 10.3389/fonc.2021.661184

Figure 2.

Figure 2

Effect of Pinocembrin (PCB) on cell cycle distribution and apoptosis in breast cancer (BC) cells. (A) MCF-7 and MDA-MB-231 cells were incubated with PCB (0, 80, 160, or 240 μM) for 72 h. Cell cycle distribution of MCF-7 and MDA-MB-231 cells was analyzed by flow cytometry, representative images were shown. The proportions of MCF-7 and MDA-MB-231 cells in G0/G1, S, and G2/M phases are presented in the histograms. *p < 0.05, **p < 0.01 vs. the control group. (B) MCF-7 and MDA-MB-231 cells were incubated with 0, 80, 160, or 240 μM PCB for 72 h. Annexin V/PI flow cytometry analysis was used to assess the proportions of apoptotic cells, which are presented in histograms. *p < 0.05, **p < 0.01 vs. the control group.