Table 3.

Regions showing significant difference in ALFF analysis between Group C and Group I at 7 days after surgery.

Cluster name	Brain region	Cluster size	MNI coordinates			Effect size	t-value
			x	y	z
Cluster 1	Left middle temporal gyrus	90	−51	−48	21	1.02	3.40
	Left precentral gyrus	72	−21	−27	54	0.69	3.35
	Left paracentral lobule	50	−12	−33	51	2.56	4.38
	Left hippocampus	28	−24	−36	1	0.91	3.09
	Left parahippocampal gyrus	26	−24	−36	−9	0.76	3.00
	Left precuneus	19	−15	−42	1	0.45	3.40
Cluster 2	Left orbital middle frontal gyrus	182	−36	60	−6	0.79	−3.77
	Left orbital superior frontal gyrus	132	−27	54	−3	0.74	−3.55
	Left medial superior frontal gyrus	98	−12	45	3	0.60	−3.09

Data are mean ± SD or frequencies.

ALFF, amplitude of low-frequency fluctuation; PND, post-operative neurocognitive disorder; MoCA, montreal cognitive assessment; T₀, 1 day before surgery; T₂, 7 days after surgery.

p < 0.05 was considered as statistically significant.