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. 2021 Jul 16;12:694243. doi: 10.3389/fimmu.2021.694243

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Copyright © 2021 Prokop, Hartog, Chesla, Faber, Love, Karam, Abualkheir, Feldmann, Teng, McBride, Leimanis, English, Holsworth, Frisch, Bauss, Kalpage, Derbedrossian, Pinti, Hale, Mills, Eby, VanSickle, Pageau, Shankar, Chen, Carcillo, Sanfilippo, Olivero, Bupp and Rajasekaran

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blood transcriptome foreign RNA signatures of SARS-CoV-2 patients. (A) Box and whisker plots for normalized reads mapped to bacteria, plants (Viridiplantae), or viruses with outlier samples labeled. (B) Top mapping values in samples for parasite (orange), bacteria (cyan), or virus (red) RNA. Values are shown as the highest (max) sample normalized counts (x-axis) for each labeled vs. the z-score for that sample (y-axis) relative to the entire cohort. (C) Box and whisker plot for normalized SARS-CoV-2 reads. Controls are gray, COVID samples cyan, and COVID/Lethal red.