TABLE 1.
Characteristics of participants who completed the resting CBF measures using TCD and MRI brain imaging modalities
| Group (n) | Younger (20) | Older (15) | p value | Younger fit (8) | Younger unfit (12) | p value | Older fit (9) | Older unfit (6) | p value |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 24.5 (6.9) | 66.5 ** (6.7) | <0.001 | 27.6 (8.1) | 22.4 (5.3) | 0.097 t | 64.2 (6.8) | 69.8 (5.4) | 0.114 |
| V̇O2max (mL·min−1·kg−1) | 43.8 (10.7) | 33.4 * (15.9) | 0.026 | 54.5 (5.0) | 36.0 ** (5.5) | <0.001 | 42.6 (13.9) | 19.7 ** (3.3) | 0.001 |
| Heart Rate (b·min−1) | 64 (8) | 57 (8) | 0.124 | 55 (7) | 70 * (15) | 0.018 | 55 (7) | 61 (8) | 0.181 |
| MAP (mm Hg) | 80 (11) | 83 (11) | 0.445 | 77 (12) | 82 (9) | 0.297 | 80 (9) | 89 (12) | 0.120 |
| Sex (male: female) | 12:8 | 10:5 | 7:1 | 5:7 | 8:1 | 2:4 |
Values represent mean (± standard deviation) obtained from ANOVAs. Age groups were defined as younger (18–40 years) and older (50–80 years), while the criterion for being fit was defined as ≥ 45 ml·min‐1·kg‐1 and ≥ 25 ml·min‐1·kg‐1 for the younger and older groups, respectively. Heart rate values are from the TCD visit.
Abbreviations: MAP, mean arterial blood pressure; V̇O2max, maximum oxygen consumption.
Significant age/fitness effects (different from younger group/ different from fit group)
t
Shows a trend toward significance: 0.05 < p ≤ 0.10
*
p ≤ .05
**
p ≤ .01