Table 2.
Radiological and laboratory findings on diagnosis among the study groups (N = 225)
| Findings | Control (n = 36) | ASA alone (n = 31) | ENX alone (n = 123) | ASA-ENX (n = 35) | p value |
|---|---|---|---|---|---|
| Total Lung Severity Score (n = 76), mean ± SD (range) | 10.9 ± 5.5 | 9.7 ± 4.0 | 14.7 ± 4.9 a | 15.3 ± 4.3 | 0.015* |
| (0–19) | (2–15) | (5–25) | (9–20) | ||
| CT Phenotype (N = 193) | (n = 18) | (n = 28) | (n = 113) | (n = 34) | |
| Type L | 10 (55.6%) | 15 (53.6%) | 42 (37.2%) | 17 (50.0%) | 0.2 |
| Type H | 8 (44.4%) | 13 (46.4%) | 71 (62.8%) | 17 (50.0%) | |
| Hemoglobin (g/dL) | 12.2 ± 1.8 | 11.5 ± 1.6 | 11.8 ± 1.9 | 11.6 ± 1.9 | 0.365 |
| White blood cells (× 1000) | 9.1 ± 7.4 | 8.6 ± 4.0 | 9.0 ± 4.5 | 9.2 ± 4.2 | 0.409 |
| Lymphocytes (%) | 25.9 ± 14.3 | 23.5 ± 16.3 | 19.7 ± 11.3 | 17.3 ± 13.4 | 0.327 |
| Platelets (× 1000) | 235.7 ± 110.4 | 210.3 ± 63.4 | 198.2 ± 80.3** | 194.1 ± 63.5 | 0.045* |
| d-Dimer (ng/mL) | 2300 ± 2700 | 1300 ± 1400 | 1200 ± 2000 | 500 ± 700 | 0.556 |
| Ferritin (ng/mL) | 451.6 ± 696.9 | 151.0 ± 146.1 | 228.4 ± 186.4 | 147.5 ± 96.9 | 0.846 |
| C-reactive protein (mg/L) | 63.6 ± 72.9 | 71.6 ± 53.5 | 48.4 ± 41.7 | 43.5 ± 31.6 | 0.377 |
| Erythrocyte sedimentation rate (mm/hour) | 31.7 ± 23.9 | 36.3 ± 31.2 | 37.4 ± 18.7 | 41.7 ± 40.2 | 0.873 |
| Albumin (g/dL) | 3.7 ± 0.8 | 3.3 ± 0.5 | 3.4 ± 0.6 | 3.5 ± 0.5 | 0.304 |
| Alanine aminotransferase (U/L) | 24.6 ± 12.0 | 31.8 ± 17.3 | 46.8 ± 42.4** | 33.8 ± 17.3 | 0.001* |
| Aspartate aminotransferase (U/L) | 25.5 ± 14.9 | 38.9 ± 20.1** | 53.5 ± 47.9** | 32.9 ± 15.7 | <0.001* |
| Bilirubin (mg/dL) | 1.0 ± 1.1 | 0.7 ± 0.2 | 0.8 ± 0.6 | 0.8 ± 0.2 | 0.752 |
| Serum creatinine (mg/dL) | 1.5 ± 1.9 | 1.5 ± 0.9 | 1.5 ± 2.7 | 1.2 ± 0.4 | 0.346 |
ASA acetylsalicylic acid, ASA-ENX both acetylsalicylic acid and enoxaparin, CT computed tomography, ENX enoxaparin
*Statistically significant p value (< 0.05); Kruskal Wallis Test and Fisher’s exact test
**Significantly different from the control group (p value adjusted for multiple comparisons with Bonferroni Correction)
aSignificantly different from the aspirin group (p value adjusted for multiple comparisons with Bonferroni Correction)