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. 2021 Jul 30;41(8):723–732. doi: 10.1007/s40261-021-01061-2

Table 3.

Logistic regression analysis for predicting thromboembolic events in the study groups (N = 225)

Variables Adjusted modela p value
OR 95% CI
Constant 0.052 < 0.001*
Age (y) 1.034 1.000–1.069 0.047*
Severe/critical COVID-19 (vs moderate) 6.008 1.570–22.99 0.009*
Comorbidities
 Diabetes mellitus (vs No) 0.867 0.367–2.051 0.746
 Hypertension (vs No) 1.740 0.704–4.301 0.230
 Established cardiovascular disease (vs No) 3.289 1.057–10.23 0.040*
Study groups (vs non-ASA and non-ENX)
 Acetylsalicylic acid alone 0.163 0.035–0.752 0.020*
 Enoxaparin alone 0.071 0.018–0.280 < 0.001*
 Both acetylsalicylic acid and enoxaparin 0.010 0.001–0.078 < 0.001*

Variables entered on step 1: Age (y), COVID-19 Severity (severe/critical vs moderate), diabetes mellitus (Y/N), hypertension (Y/N), established cardiovascular disease (Y/N), and study groups (vs non-acetylsalicylic acid and non-anticoagulant)

ASA acetylsalicylic acid, CI confidence interval, ENX enoxaparin, OR odds ratio

*Statistically significant p value (< 0.05)

aBinary Logistic Regression Model: Hosmer and Lemeshow χ2 (df) = 5.926 (8), p = 0.655; Negelkerke R Square = 0.310; Overall correct classification = 83.9%