FIGURE 1:

Study design.

^aParticipants began a standardized diet of 920 mg or 40 mmol (±10%) Na⁺ and 5005 mg or 128 mmol (±10%) K⁺ per day (continued until study Day 9). ^bSZC was administered to two dose groups (5 or 10 g QD). ^cParticipants discharged from clinic at study Day 9. ^dDefined as nothing by mouth except water for ≥8 h prior to collection of any sample.