Skip to main content
. 2021 Jul 18;7(7):1183–1190. doi: 10.1021/acscentsci.1c00351

Figure 1.

Figure 1

LC-MS/MS characterization of numerous RNA modifications in the Aplysia CNS. (A) Extracted ion chromatograms for modified nucleosides (±0.01 m/z) in the pedal ganglion: m1A, Am, m6A (m/z 282.12); m3C, m5C, Cm (m/z 258.11); m7G, Gm, m2G (m/z 298.12); m4Cm (m/z 272.13); m2,2,7G (m/z 326.15); m2,2G (m/z 312.13), m6,6A (m/z 296.14); mcm5s2U (m/z 333.08); and i6A (m/z 336.17). The inset shows the MS/MS spectrum used to positively identify mcm5s2U. (B) PCA score and (C) loading plots using 13 total RNA modifications in Aplysia ganglia.