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. 2021 Jul 29;21:869. doi: 10.1186/s12885-021-08606-w

Table 1.

Baseline characteristics and surgery rate according to dependent variables

Patients not requiring surgery (n = 15,545) Surgery (n = 162) Surgery rate % (95% CI) Significancea
Sex (n = 15,707) • Female 6708 (43.2%) 72 (44.4%) 1.06 (0.82–1.31) 0.7
• Male 8837 (56.8%) 90 (55.6%) 1.01 (0.80–1.22)
Age (n = 15,707) • < 60 years 6855 (44.1%) 48 (29.6%) 0.69 (0.50–0.89) < 0.001
• ≥60 years 8690 (55.9%) 114 (70.4%) 1.29 (1.06–1.53)
PS (n = 15, 383) • 0 12,388 (81.3%) 132 (83.0%) 1.05 (0.87–1.23) 0.8
• 1 2836 (18.6%) 27 (17.0%) 0.94 (0.59–1.29)
ASA (n = 15,383) • I 8876 (58.2%) 96 (60.3%) 1.07 (0.86–1.28) 0.9
• II 5391 (35.4%) 53 (33.3%) 0.97(0.71–1.23)
• III 957 (6.3%) 10 (6.3%) 1.03 (0.40–1.67)
Fecal Hb (n = 15,707) • < 100 μg/g 10,388 (66.8%) 79 (48.8%) 0.75 (0.59–0.92) < 0.001
• 100–200 μg/g 2935 (18.9%) 41 (25.3%) 1.42 (0.99–1.86)
• > 200 μg/g 2222 (14.3%) 42 (25.9%) 1.85 (1.30–2.41)
N.colonoscopies (n = 15,707) • One 13,557 (87.2%) 122 (75.3%) 0.89 (0.73–1.05) < 0.001
• At least two 1988 (12.8%) 40 (24.7%) 1.97 (1.37–2.58)
Number of polyps (n = 15,707) 2 (IQR 1–4) 3 (IQR 1–5) < 0.001
Number of adenomas (n = 15,707) 1 (IQR 0–3) 2 (IQR 1–4) < 0.001
Adenoma size (mm) (n = 15,707) 5 (IQR 0–12) 19 (IQR 8–31.3) < 0.001
European guidelines classification (n = 15,707) • No adenoma 4650 (29.9%) 4 (2.5%) 0.08 (0.00–0.17) < 0.001
• Low risk 3626 (23.3%) 4 (2.5%) 0.11 (0.00–0.22)
• Intermediate risk 4179 (26.9%) 17 (10.5%) 0.40 (0.21–0.59)
• High risk 3090 (19.9%) 137 (84.6%) 4.24 (3.55–4.94)
Endoscopist’s ADR (n = 15,459) • Q1 (≤60%) 2653 (17.3%) 42 (26.1%) 1.56 (1.09–2.03) 0.02
• Q2 (60–65.3%) 3989 (26.1%) 40 (24.8%) 0.99 (0.67–1.30)
• Q3 (65.3–70.8%) 4181 (27.3%) 34 (21.1%) 0.81 (0.54–1.08)
• Q4 (> 70.8%) 4474 (29.2%) 45 (28.0%) 0.99 (0.71–1.28)
Endoscopist’s number of colonoscopies (n = 15,459) • Q1 (≤57) 198 (1.3%) 2 (1.2%) 1.00 (−0.38–2.38) 0.03
• Q2 (58–278) 1647 (10.8%) 18 (11.2%) 1.08 (0.58–1.58)
• Q3 (279–507) 5340 (34.9%) 39 (24.2%) 0.72 (0.50–0.95)
• Q4 (> 507) 8113 (53.0%) 102 (63.4%) 1.24 (1.00–1.48)
Complexity of hospital (n = 15,707) • Third level 7150 (46.0%) 52 (32.1%) 0.72 (0.53–0.92) < 0.001
• Second level 8395 (54.0%) 110 (67.9%) 1.29 (1.05–1.53)

ADR Adenoma detection rate, ASA American Society of Anesthesiologists’ Physical Status, CI Confidence interval, Hb Hemoglobin, IQR Interquartile range, PS Performance status

aSignificance in the univariant analysis using the Chi-square test for qualitative variables and the Student’s t test for cuantitative variables