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Lifespan increase in different cellular models cultured under different oxygen concentrations
| Cellular model | O2 concentration | Lifespan increase | Reference |
|---|---|---|---|
| IMR90, WI38 | 2 and 10% | 25% | Packer et al. Nature, 1977 |
| IMR90 | 1, 6 and 12% | 22% | Saito et al. Exp. Cell Research, 1995 |
| Mouse embryonal fibroblasts (MEFs) | 3% | 500% | Parrinello et al. Nature Cell Biology, 2003 |
| Bovine embryonal fibroblasts (BFF) | 2% | 80% | Betts et al. Biogerontology, 2008 |
