Table 5.
Sensitivity analyses for OR of detection in cases compared with controls, by pathogen, adjusted for age and season (logistic regression)
Pathogen |
Additionally adjusted for country of inclusion | Excluding mildly symptomatic controls | ||||
Adjusted OR | 95% CI | P value | Adjusted OR | 95% CI | P value | |
Streptococcus pneumoniae | 1.63 | 1.17 to 1.27 | 0.003 | 1.95 | 1.39 to 2.73 | <0.001 |
RSV | 20.7 | 9.38 to 45.82 | <0.001 | 42.6 | 13.31 to 136.29 | <0.001 |
Influenza virus | 6.38 | 2.56 to 15.88 | <0.001 | 6.38 | 2.42 to 16.81 | <0.001 |
Parainfluenza virus | 4.87 | 1.93 to 12.28 | 0.001 | 4.02 | 1.63 to 9.96 | 0.003 |
Metapneumovirus | 4.04 | 1.10 to 14.79 | 0.035 | 6.20 | 1.37 to 28.02 | 0.018 |
No pathogen detected | 0.12 | 0.07 to 0.22 | <0.001 | 0.10 | 0.05 to 0.18 | <0.001 |
P values were obtained by Wald test.
RSV, respiratory syncytial virus.