Table 1.
Differentially expressed exosomal microRNAs identified by next generation sequencing.
| miRNA Information | Statistics & Regulation | ||||
|---|---|---|---|---|---|
| Source | Mature-miRNA | sequence | Fold Change | P-value | Regulation |
| Serum | hsa-miR-130b-3p | CAGUGCAAUGAUGAAAGGGCAU | 4.555389982 | 0.036615174 | Up |
| Serum | hsa-miR-143-3p | UGAGAUGAAGCACUGUAGCUC | -2.481915254 | 0.043638531 | Down |
| Serum | hsa-miR-151a-3p | CUAGACUGAAGCUCCUUGAGG | 2.545806244 | 0.013604136 | Up |
| Serum | hsa-miR-15b-3p | CGAAUCAUUAUUUGCUGCUCUA | 5.095125215 | 0.016185555 | Up |
| Serum | hsa-miR-194-5p | UGUAACAGCAACUCCAUGUGGA | -2.508236592 | 0.046425407 | Down |
| Serum | hsa-miR-196b-5p | UAGGUAGUUUCCUGUUGUUGGG | -4.002942023 | 0.038692865 | Down |
| Serum | hsa-miR-22-5p | AGUUCUUCAGUGGCAAGCUUUA | -5.970168823 | 0.034517425 | Down |
| Serum | hsa-miR-6087 | UGAGGCGGGGGGGCGAGC | -2.154113907 | 0.019948851 | Down |
| Urine | hsa-miR-1246 | AAUGGAUUUUUGGAGCAGG | 5.747077844 | 0.043731253 | Up |
| Urine | hsa-miR-139-5p | UCUACAGUGCACGUGUCUCCAGU | -6.184723327 | 0.025724708 | Down |
| Urine | hsa-miR-345-5p | GCUGACUCCUAGUCCAGGGCUC | -7.376130587 | 0.021140159 | Down |
Fold change, Fold change between two groups; P-value, P-value is calculated by paired t-test; Regulation, ‘up’ indicates up-regulation, and ‘down’ indicates down-regulation.