Table 2:

Distribution of Observed Symptoms and Substance Use in 19,088 Clinic Visits

	All Visits		Last Visit per Participant
	NNDC (4,342 visits)	JHHCC (5,409 visits)	NNDC (708 visits)	JHHCC (1,205 visits)
PHQ*, mean (SD)	10.9 (7.2)	3.4 (4.5)	10.5 (7.1)	3.4 (4.5)
	(n=4,008)	(n=5,138)	(n=648)	(n=1,166)
GAD-7†, mean (SD)	8.5 (6.3)	2.2 (4.2)	8.3 (6.2)	2.2 (4.2)
	(n=3,982)	(n=2,868)	(n=636)	(n=592)
ASRM‡, mean (SD)	2.5 (3.0)	N/A	2.4 (3.0)	N/A
	(n=3,884)		(n=602)
AUDIT-C§, mean (SD)	N/A	1.3 (2.0)	N/A	1.3 (2.0)
		(n=5,363)		(n=1,197)
Heroin Use, % (n)	N/A	6.4% (272)	N/A	5.0% (271)
		(n=4,272)		(n=1,193)
Cocaine Use, % (n)	N/A	11.4% (520)	N/A	9.6% (519)
		(n=4,566)		(n=1,196)
Days Since Prior Visit with Symptoms Recorded, median [IQR]	33 [14 to 78]	91 [46 to 133]	33 [14 to 78]	91 [47 to 133]

All participants were used in fitting models. Only participants with >1 clinic visit were used in validating the algorithm.

^*PHQ = Patient Health Questionnaire (9-item scale for NNDC ranges from 0–27, 8-item scale for JHHCC ranges from 0–24).

^†GAD-7 = Generalized Anxiety Disorder scale (range 0–21).

^‡ASRM = Altman Self-Rating Mania Scale (range 0–20).

^§AUDIT-C = Alcohol Use Disorders Identification Test consumption questions (range 0–12).