Table 3.
Comparative analysis of patients with lactate level >5 mmol/l and patients with lactate <5 mmol/l
| Variables | DKA group with lactate ≥5 mmol/l (n=10) (mean±SD) 95% CI | DKA group with lactate <5 mmol/l (n=52) (mean±SD) 95% CI | P |
|---|---|---|---|
| Age (years) | 22.30±15.47 (11.23-33.37) | 27.21±16.31 (22.67-31.75) | 0.383 |
| Duration of DM (years) | 4.60±3.59 (2.02-7.17) | 2.84±3.78 (1.79-3.90) | 0.181 |
| Hospital stay (days) | 8.90±3.72 (6.23-11.56) | 7.59±3.76 (6.54-8.64) | 0.319 |
| Initial plasma glucose (mg/dl) | 627±97 (557-695) | 520±152 (477-562) | 0.038* |
| SBP (mmHg) | 90±19 (76-103) | 108±11 (105-111) | 0.000* |
| DBP (mmHg) | 60±7 (54-65) | 69±10 (66-71) | 0.015* |
| APACHE II score | 12.80±4.34 (9.69-15.90) | 9.38±3.44 (8.4210.34) | 0.008* |
| PH | 6.94±0.13 (6.85-7.04) | 7.08±0.15 (7.03-7.12) | 0.014* |
| Bicarbonate (HCO3) | 5.28±3.51 (2.76-7.79) | 6.59±3.51 (5.61-7.56) | 0.284 |
| Lactate | 6.04±1.35 (3.21-4.26) | 2.25±0.71 (2.81-4.76) | 0.000 |
| Severity of DKA | |||
| Mild, n (%) | 1 (10) | 15 (29) | 0.430 |
| Moderate, n (%) | 1 (10) | 20 (38) | 0.143 |
| Severe DKA, n (%) | 8 (80) | 17 (33) | 0.007* |
| Metformin use, n (%) | 2 (20) | 13 (25) | 0.735 |
| Morbidity | |||
| AKI, n (%) | 3 (30) | 10 (19) | 0.424 |
| Hypotension, n (%) | 4 (40) | 5 (10) | 0.034* |
| Respiratory, cardiac and cardiovascular complications, and cerebral edema. | 0 | 0 | |
| Mortality | 0 | 0 |
Categorical data are shown as %; continuous variables are shown as mean±standard deviation. CAD, coronary artery disease; AKI, acute kidney injury; SBP; systolic blood pressure; DBP, diastolic blood pressure; CI, confidence interval; * Significant