Table 4.
Univariate logistic regression analysis for post-TIPS mortality within 60 days
Predictors for development of HE within 60 d | History of pre-TIPS HE | No history of pre-TIPS HE | ||||||
n | OR | P | 95% CI | n | OR | P | 95% CI | |
Age ≥65 yr | 125 | 2.63 | 0.027 | 1.11–6.23 | 76 | 2.45 | 0.072 | 0.92–6.53 |
Male vs female | 125 | 1.05 | 0.884 | 0.52–2.16 | 76 | 0.94 | 0.900 | 0.37–2.40 |
Stent type: traditional vs controlled expansion | 125 | 1.61 | 0.233 | 0.74–3.50 | 76 | 0.69 | 0.525 | 0.22–2.17 |
MELD score | 124 | 1.04 | 0.109 | 0.99–1.10 | 75 | 1.01 | 0.748 | 0.94–1.09 |
MELD-Na score | 124 | 1.02 | 0.472 | 0.97–1.07 | 75 | 1.01 | 0.716 | 0.95–1.08 |
Child-Pugh score | 124 | 1.49 | 0.007 | 1.12–1.99 | 74 | 0.77 | 0.398 | 0.42–1.41 |
≥1 admission for HE within 6 mo pre-TIPS | 125 | 1.90 | 0.192 | 0.72–4.96 | 0 | — | — | — |
≥1 ICU admission for HE within 6 mo pre-TIPS | 125 | 1.82 | 0.429 | 0.41–7.95 | 0 | — | — | — |
PV pressure | 120 | 1.05 | 0.151 | 0.98–1.11 | 75 | 1.05 | 0.233 | 0.97–1.15 |
RA pressure | 119 | 1.03 | 0.410 | 0.96–1.11 | 74 | 0.95 | 0.308 | 0.85–1.05 |
PSPG | 123 | 1.04 | 0.240 | 0.97–1.12 | 75 | 1.05 | 0.321 | 0.95–1.16 |
AST | 125 | 0.99 | 0.395 | 0.98–1.01 | 75 | 1.00 | 0.465 | 0.99–1.00 |
ALT | 125 | 1.01 | 0.421 | 0.99–1.03 | 75 | 1.00 | 0.514 | 0.99–1.01 |
Sodium | 125 | 1.07 | 0.090 | 0.99–1.15 | 76 | 1.00 | 0.929 | 0.91–1.09 |
Albumin | 125 | 1.08 | 0.766 | 0.64–1.82 | 73 | 1.08 | 0.854 | 0.49–2.36 |
Bilirubin (total) | 125 | 1.06 | 0.160 | 0.98–1.15 | 75 | 0.56 | 0.049 | 0.31–1.00 |
Creatinine | 125 | 1.95 | 0.020 | 1.11–3.42 | 76 | 1.21 | 0.390 | 0.78–1.88 |
Blood urea nitrogen | 121 | 1.01 | 0.365 | 0.99–1.03 | 74 | 1.02 | 0.127 | 0.99–1.06 |
Body weight | 120 | 0.99 | 0.231 | 0.99–1.00 | 75 | 0.99 | 0.061 | 0.98–1.00 |
INR | 123 | 1.63 | 0.383 | 0.55–4.85 | 76 | 0.65 | 0.767 | 0.04–11.1 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CI, confidence interval; HE, hepatic encephalopathy; ICU, intensive care unit; INR, international normalized ratio; MELD, model for end-stage liver disease; OR, odds ratio; PSPG, portosystemic pressure gradient; PV, portal vein; RA, right atrium; TIPS, transjugular intrahepatic portosystemic shunt.