Fig. 6. 3D margin assessment of breast specimens using automated depth-averaged Raman spectroscopy. (A) Photograph of the breast specimen which includes fatty margins. (B) Margins of the specimen as rendered by the 3D-scanner. (C) H&E section from a biopsy spot taken from the fatty margin (10× magnification). (D–F) Describe the corresponding figures for a breast specimen with fibroadenomatoid margins. (F) An increase in fibro-epithelial composition can be observed at a depth of 0.5–1.5 mm from the margin. Reproduced from ref. 101 with permission from Nature Research, copyright 2017.
