Summary of pharmacologically active compounds from Tian Ma and Jiang Can detected in 20 V DART-MS analysis of powdered product and extracts and corresponding reported biological activity of the compounds. [–H] adducts were detected in negative ionization mode. * designates M − OH adduct. Bolded compounds are reported main pharmacologically active compounds.
| # | Compound | Biological activity | Adduct | Adduct mass | Extraction method | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Powder | H2O | EtOH | MAE | EtOH : CHCl3 | Acid wash | |||||
| Tian Ma | ||||||||||
| 1* | 4-Hydroxybenzyl alcohol | Suppress dopaminergic & serotonergic activity37 | –OH | 107.0497 | X | X | X | X | X | |
| 2 | Vanillin | Anti-inflammatory8 | –H | 151.0395 | X | X | ||||
| 3* | Vanillyl alcohol | Suppress oxidative stress38 | –OH | 137.0603 | X | X | X | X | ||
| 4 | Vanillic acid | Inhibits inflammatory pain39 | –H | 167.0344 | X | X | ||||
| 5* | Gastrodin | Anti-depressant40 | –OH | 269.1025 | X | X | X | |||
| Jiang Can | ||||||||||
| 1 | d-Mannitol | Diuretic41 | +H | 183.0869 | X | X | X | X | X | |
| 2 | Citric acid | Antioxidant42 | –H | 191.0192 | X | X | X | X | ||
| 3* | β-Sitosterol | Anticonvulsant11 | –OH | 397.3834 | X | X | ||||