Fig. 6. Biosynthetic gene clusters of microcin C-like compounds found across bacterial genomes. Clusters containing minimal sets of genes required for the production of peptidyl-adenylates and peptidyl-cytidylates are shown on red and green background, respectively. The archetypal and best-studied mcc BGC from the E. coli pMccC7 plasmid is shown on blue background. The number of amino acid residues in precursor peptides is indicated near the A genes. Genes involved (or proposed to be involved) in self-immunity are indicated with asterisks. Known functions for some gene products are listed in the right. Genes with no identified function are shown in grey. cyt P450 – cytochrome P450, HIT – histidine triad, MTase – methyltransferase.