Table 2:
Extracellular Matrix proteins identified in the mouse lens fiber mass based on proteomics analysis.
| Protein Name | Accession No. | Alternate ID | MW (kDa) | Peptide# (unique) | % Coverage |
|---|---|---|---|---|---|
| Basement membrane-specific heparan sulfate proteoglycan core protein (Perlecan) | PGBM | Hspg2 | 398 | 42 | 15 |
| Laminin subunit gamma 1 | LAMC1 | Lamc1 | 177 | 16 | 13 |
| Laminin subunit beta 1 | LAMB1 | Lamb1 | 197 | 17 | 13 |
| Laminin subunit alpha 2 | LAMA2 | Lama2 | 344 | 5 | 2 |
| Nidogen-1 | NID1 | Nid1 | 136 | 27 | 27 |
| Nidogen-2 | NID2 | Nid2 | 154 | 6 | 6 |
| Collagen alpha 2(IV) chain | CO4A2 | Col4a2 | 167 | 10 | 9 |
| Collagen alpha 1(IV) chain | CO4A1 | Col4a1 | 161 | 8 | 7 |
| Collagen alpha 2(I) chain | CO1A2 | Col1a2 | 129 | 2 | 1 |
| Collagen alpha 1(XII) chain | COCA1 | Col12a1 | 340 | 2 | 1 |
| Collagen alpha 4(VI) chain | CO6A4 | Col6a4 | 251 | 2 | 1 |
| Collagen alpha 1(XXIV) chain | COOA1 | Col24a1 | 175 | 2 | 1 |
| Collagen alpha 1(XVIII) chain | COIA1 | Col18a1 | 182 | 2 | 2 |
| Extracellular matrix protein FRAS1 | FRAS1 | Fras1 | 442 | 2 | 0.1 |