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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Transl Stroke Res. 2021 Jan 21;12(6):1045–1054. doi: 10.1007/s12975-021-00892-7

Fig. 3. CD38 - cADPR signals increase extracellular mitochondria via ryanodine receptor:

Fig. 3.

Extracellular mitochondria were identified by mitochondrial protein E1 alpha pyruvate dehydrogenase labeled by GFP. a-b. FACS analysis showed that NAD treatment for 24 hrs increased extracellular mitochondrial GFP events and co-treatment with Dantrolene diminished the effects (Control; n= 7, NAD; n= 6, NAD + Dantrolene; n=5). c. All conditions did not influence cell viability (n=4). *P<0.05, one-way ANOVA followed by Fisher’s LSD test. All values are mean +/− SD.