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. 2021 Jul 16;12:724741. doi: 10.3389/fimmu.2021.724741

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Copyright © 2021 Liu, Zhou, Yuan, Gao, Kui, Liu and Pei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlations of NPM1 expression with glycolysis related genes in lung adenocarcinoma (LUAD). (A) GSE31210 and TCGA LUAD data sets analyzed the correlation between the NPM1 and the m6A related genes expression in LUAD. (B) Draw a scatter plot to show the correlation between the NPM1 and the glycolysis related genes expression, include ENO1, G6PD, HK2, LDHA, LDHB, PDK3, PGK1 and SLC2A1. (C) The differential expression of glycolysis related genes between high and low NPM1 expression groups in LUAD tumor samples. (D) Venn diagram showed both expression correlation and differential expression of genes, including ENO1, HK2, LDHA, LDHB, PGK1 and SLC2A1. (E) Kaplan-Meier curve of ENO1, HK2, LDHA, LDHB, PGK1 and SLC2A1. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. ns, not significant.