Table 2.
Correlation analysis between NPM1 and immune cell marker gene in TIMER, GEPIA and TCGA.
| Description | Gene markers | TIMER | GEPIA | TCGA | |||
|---|---|---|---|---|---|---|---|
| Purity | Tumor | Tumor | |||||
| rho | P | rho | P | rho | P | ||
| B cell | CD19 | -0.197 | 1.08E-05 | -0.24 | 5.00E-08 | -0.193 | 6.86E-06 |
| MS4A1 | -0.149 | 9.01E-04 | -0.18 | 6.70E-05 | -0.184 | 1.88E-05 | |
| CD79A | -0.189 | 2.39E-05 | -0.26 | 1.20E-08 | -0.169 | 8.43E-05 | |
| CD8+ T Cell | CD8A | 0.013 | 7.69E-01 | 0.0061 | 8.90E-01 | 0.048 | 2.67E-01 |
| CD8B | -0.013 | 7.68E-01 | -0.016 | 7.30E-01 | 0.037 | 3.99E-01 | |
| IL2RA | 0.099 | 2.81E-02 | 0.15 | 1.20E-03 | 0.111 | 1.04E-02 | |
| Tfh | CXCR3 | -0.134 | 2.79E-03 | -0.14 | 2.70E-03 | -0.050 | 2.51E-01 |
| CXCR5 | -0.168 | 1.83E-04 | -0.39 | 3.50E-09 | -0.130 | 2.63E-03 | |
| ICOS | -0.006 | 8.89E-01 | 0.019 | 6.70E-01 | -0.023 | 5.99E-01 | |
| Th1 | IL12RB1 | -0.103 | 2.23E-02 | -0.082 | 7.30E-02 | -0.070 | 1.04E-01 |
| CCR1 | -0.019 | 6.69E-01 | 0.05 | 2.70E-01 | 0.045 | 2.97E-01 | |
| CCR5 | -0.037 | 4.11E-01 | 0.0054 | 9.10E-01 | -0.019 | 6.56E-01 | |
| Th2 | CCR4 | -0.031 | 4.93E-01 | 0.02 | 6.60E-01 | -0.061 | 1.56E-01 |
| CCR8 | 0.029 | 5.18E-01 | 0.091 | 4.60E-02 | 0.023 | 6.03E-01 | |
| HAVCR1 | 0.080 | 7.72E-02 | 0.088 | 5.20E-02 | 0.046 | 2.93E-01 | |
| Th17 | IL21R | -0.087 | 5.23E-02 | -0.064 | 1.60E-01 | -0.079 | 6.81E-02 |
| IL23R | 0.012 | 7.97E-01 | 0.097 | 3.30E-02 | -0.088 | 4.15E-02 | |
| CCR6 | -0.095 | 3.43E-02 | -0.0089 | 8.50E-01 | -0.103 | 1.73E-02 | |
| Treg | FOXP3 | -0.054 | 2.35E-01 | -0.057 | 2.10E-01 | 0.011 | 8.00E-01 |
| NT5E | 0.104 | 2.12E-02 | 0.16 | 3.20E-04 | 0.162 | 1.72E-04 | |
| IL7R | -0.008 | 8.53E-01 | 0.022 | 6.30E-01 | -0.067 | 1.21E-01 | |
| T cell exhaustion | PDCD1 | -0.071 | 1.15E-01 | -0.087 | 5.50E-02 | -0.018 | 6.74E-01 |
| CTLA4 | -0.067 | 1.39E-01 | -0.089 | 5.20E-02 | -0.091 | 3.49E-02 | |
| LAG3 | -0.141 | 1.74E-03 | -0.19 | 2.50E-05 | -0.072 | 9.61E-02 | |
| M1 Macrophage | NOS2 | -0.080 | 7.50E-02 | -0.008 | 8.60E-01 | 0.007 | 8.81E-01 |
| IRF5 | -0.223 | 5.80E-07 | -0.14 | 1.40E-03 | -0.095 | 2.83E-02 | |
| PTGS2 | -0.051 | 2.56E-01 | -0.053 | 2.50E-01 | -0.060 | 1.68E-01 | |
| M2 Macrophage | CD163 | 0.009 | 8.38E-01 | 0.048 | 2.90E-01 | 0.036 | 4.09E-01 |
| MRC1 | 0.011 | 8.14E-01 | 0.12 | 1.00E-02 | 0.029 | 5.03E-01 | |
| CD209 | 0.016 | 7.15E-01 | 0.11 | 2.10E-02 | 0.052 | 2.30E-01 | |
| TAM | CCL2 | -0.001 | 9.74E-01 | 0.0077 | 8.70E-01 | 0.071 | 1.02E-01 |
| CD86 | -0.021 | 6.36E-01 | 0.053 | 2.40E-01 | 0.046 | 2.87E-01 | |
| CD68 | -0.055 | 2.24E-01 | 0.088 | 5.30E-02 | 0.034 | 4.30E-01 | |
| Monocyte | CD14 | -0.095 | 3.41E-02 | -0.046 | 3.20E-01 | 0.050 | 2.50E-01 |
| CD33 | -0.062 | 1.66E-01 | -0.0073 | 8.70E-01 | 0.005 | 9.12E-01 | |
| ITGAX | -0.197 | 9.99E-06 | -0.17 | 1.60E-04 | -0.179 | 3.32E-05 | |
| Natural killer cell | B3GAT1 | -0.138 | 2.11E-03 | -0.12 | 6.70E-03 | -0.153 | 3.79E-04 |
| KIR3DL1 | -0.158 | 4.36E-04 | -0.11 | 2.10E-02 | -0.091 | 3.62E-02 | |
| CD7 | -0.205 | 4.28E-06 | -0.23 | 3.50E-07 | -0.096 | 2.57E-02 | |
| Neutrophil | FCGR3A | 0.034 | 4.56E-01 | 0.096 | 3.50E-02 | 0.092 | 3.36E-02 |
| CD55 | -0.059 | 1.94E-01 | 0.058 | 2.00E-01 | 0.053 | 2.21E-01 | |
| ITGAM | -0.090 | 4.46E-02 | -0.029 | 5.20E-01 | -0.038 | 3.81E-01 | |
| Dendritic cell | CD1C | -0.069 | 1.27E-01 | -0.008 | 8.60E-01 | 0.012 | 7.77E-01 |
| THBD | -0.010 | 8.22E-01 | 0.087 | 5.60E-02 | 0.065 | 1.33E-01 | |
| NRP1 | 0.019 | 6.80E-01 | 0.12 | 9.40E-03 | 0.040 | 3.52E-01 | |
Bold values indicate P < 0.05.