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Effect of HIF-1α RNAi combined with ASP on the migration and angiogenesis of SK-Hep1 and Hep-3B cells. (a)-(b) Invasion of HCC cells (A. transwell assay; B. transwell invasion assay with Matrigel). ∗∗P < 0.01 and ∗∗∗P < 0.001 versus control group. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus LV-shHIF1α + ASP group. (c)-(d) Angiogenesis of HCC cells. ∗∗∗P < 0.001 versus control group. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus LV-shHIF1α + ASP group.
