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. 2021 Jul 30;25:268. doi: 10.1186/s13054-021-03697-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Pooled intra-hospital mortality of patients assisted through noninvasive respiratory support outside the intensive care unit, net of the patients subjected to limitations of care. The vertical dotted line refers to the summary estimate for intra-hospital mortality of patients assisted through noninvasive respiratory support outside intensive care unit, excluding the patients subjected to limitations of care. Red squares indicate the individual study estimates of the overall intra-hospital mortality of patients assisted through noninvasive respiratory support outside the intensive care unit, excluding the patients subjected to limitations of care, whereas the black horizontal lines indicate the 95% confidence interval of single studies. The diamond refers to the summary estimate with 95% confidence interval