Fig. 2 |. Transcriptionally distinct glial subsets in the adult enteric nervous system.

Distinct subsets of enteric glia display unique transcriptional profiles in the enteric nervous system. Data from single-cell sequencing experiments indicate the presence of distinct glial populations that vary according to location along the gastrointestinal tract and species. The mouse ileum exhibits seven glial populations according to data from Zeisel et al.²⁵ (part a) and two glial subpopulations according to data from Drokhlyansky et al.²⁶ (part b). The mouse colon displays three glial subsets according to data from Drokhlyansky et al.²⁶ (part c) and the human colon displays six glial subsets (part d; also data from Drokhlyansky et al.). tSNE, t-distributed stochastic neighbour embedding. Part a was adapted from REF.²⁵, CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Parts b–d were adapted with permission from REF.²⁶, Elsevier.