Table 1.

Most common^a reported causes of death in the global pharmacovigilance database

Events	Pharmacovigilance reporting rateb
Renal failure	34 (2.80)
Myocardial infarction	33 (2.70)
Cardiac arrest	26 (2.14)
Cardiac failurec	15 (1.23)
Cardiac disorders	10 (0.82)
Congestive cardiac failured	10 (0.82)
Cerebrovascular accident	9 (0.74)
End-stage renal disease	9 (0.74)

Data are presented as n (%)

PY patient-years

^aReported in ≥ 0.5% of 1214 deaths. Of the 1214 reported deaths in the patiromer global pharmacovigilance database, 80% had no reported cause

^bReporting rate = (# events/# PY [45,000]) × 100 = % of events per 100 PYs. Between January 2016 and September 2019, there were an estimated 45,000 PYs of exposure to patiromer in the global pharmacovigilance database

^cIncludes verbatim terms of heart failure, cardiac failure, cardiac failure (not otherwise specified), cardiac function failure, and cardiac failure aggravated

^dIncludes verbatim terms of congestive heart failure, congestive cardiac failure, cardiac failure congestive, and cardiac failure congestive aggravated