Patiromer (Veltassa®, Vifor Pharma, Inc.) is a sodium-free, nonabsorbed, potassium binder that was initially approved by the US FDA in 2015 and in the EU/European Economic Area in 2017 and is now approved in many countries worldwide.

Reported adverse events from patients prescribed patiromer for hyperkalemia management collected between January 2016 and September 2019 in the global pharmacovigilance database were analyzed; the total number of individual case reports was 17,823.

The tolerability and safety profile of patiromer in clinical practice was consistent with that observed in clinical trials, supporting a predictable risk-benefit profile with no evidence of any new safety signals to date.