Table 1.
Patient characteristics and fertility preservation cycle outcomes according to type of cryopreservation method used
| COS-FP | IVM-FP | |||||
|---|---|---|---|---|---|---|
| OO-COS | ZYG-COS | All COS-FP | OO-IVM | ZYG-IVM | All IVM-FP | |
| Female patients | 6 | 9 | 15 | 15 | 10 | 25 |
| Oocyte retrievals | 8 | 14 | 22 | 16 | 10 | 26 |
| Age (years) | 35.5 [28.7–38.25] | 36.0 [31.0–39.5] | 36.0 [30.0–38.0] | 33.0 [31.0–36.0] | 37.0 [33.5–38.0] | 34.0 [32.0–37.0] |
| AMH (ng/ml) | 1.5 [0.6–2.2] | 3.9 [2.1–5.1] | 2.2 [1.3–4.7] | 3.5 [2.8–6.6] | 2.3 [1.5–5.9] | 3.2 [1.6–6.2] |
| AFC | 15.5 [10.8–17.5] | 19.0 [11.5–24.5] | 16.0 [11.0–23.0] | 17.0 [12.5–26.5] | 14.0 [12.0–18.0] | 15.0 [12.0–22.0] |
| Stimulation duration (days) | 12.5 [11.2–14.0] | 11.5 [10.8–13.0] | 12.0 [11.0–13.0] | - | - | - |
| Total FSH dose (IU) | 3300 [3000–3900] | 2550 [1772–3600] | 3000 [2081–3600] | - | - | - |
| E2 level on HCG injection day (pg/ml) | 336.0 [188.0–1001] | 1710 [920.0–3005] | 1034 [342.5–2071] | - | - | - |
|
Retrieved oocytes (total no.) |
6.0 [4.3–8.5] (49.0) |
9.5 [6.7–13.2] (145.0) |
8.0 [5.7–10.7] (194) |
8.0 [5.0–12.5] (145.0) |
4.5 [3.5–7.5] (51.0) | 6.5 [4.0–9.0] (196) |
|
Mature oocytes (total no.) |
5.5 [4.2–7.7] (44.0) |
6.0 [4.7–11.0] (104.0) |
6.0 [4.7–8.5] (148) |
6.0 [4.0–7.7] (98.0) |
4.0 [2.7–5.2] (40.0) | 5.0 [3.0–7.0] (138.0) |
| Fertilization rate* | - | 72.2% | - | - | 65.0% | - |
| Oocytes or zygotes cryopreserved/patient | 7.5 [5.7–8.5] | 6.0 [5.0–12.0] | 7.0 [5.0–10.0] | 6.0 [4.0–8.0] | 3.0 [1.0–3.2] | 4.0 [3.0–7.0] |
Data are expressed as Medians interquatile range (25th percentile–75th percentile)
AFC antral follicles count, COS controlled ovarian stimulation, FP fertility preservation, IVM in vitro maturation, OO-COS oocytes cryopreserved after COS, OO-IVM oocytes cryopreserved after IVM, ZYG-COS zygotes cryopreserved after COS, ZYG-IVM zygotes cryopreserved after IVM, no. number of *Fertilization rate: number of oocytes successfully fertilized divided by the number of mature oocytes