Table 2.

Thawing cycle characteristics and embryo transfer outcomes

	COS-FP			IVM-FP
	OO-COS	ZYG-COS	All COS-FP	OO-IVM	ZYG-IVM	All IVM-FP
Female-patients	6	9	15	15	10	25
Thawing cycles	7	14	21	18	10	28
Age (years)	40.0 [33.0–42.0]	37.5 [34.8–42.0]	38.0 [34.5–42.0]	39.0 [37.0–41.0]	40.5 [39.8–42.0]	39.0 [37.5–41.5]
Time from FP cycle to thawing (years)	3.0 [2.7–4.0]	3.0 [1.7–5.0]	3.0 [2.5–4.0]	5.0 [5.0–6.0]	5.0 [3.0–5.0]	5.0 [4.2–5.7]
Oocytes or zygotes warmed/patient (total no.)	7.5 [5.7–8.5] (44)	6.0 [4.0–9.0] (61)	7.0 [5.0–10.0] (105)	6.0 [4.0–8.0] (98)	3.0 [1.0–3.2] (26)	4.0 [3.0–7.0]
No. oocytes or zygotes still frozen	0	14	14	0	0	0
Survival rate slow freezing vitrification	-	54.3%	54.3%	54.5%	73.1%	59.2%
	72.7%	69.2%	71.4%	76.2%	-	76.2%
Fertilization rate*	68.8%	-	-	49.1%	-	-
No. embryos obtained	20	33	53	20	16	36
Percentage of good quality embryos (total no.)	25% (5)	12% (4)	17% (9)	0	13% (2)	5.5% (2)
No. embryo transfers	6	13	19	8	9	17
No. embryos transferred	9	22	31	11	12	23
Implantation rate**	11.1% (1/9)	18.2% (4/22)	16.1% (5/31)	18.2% (2/11)	8.3% (1/12)	13% (3/23)
No. live births	1	4	5	2	1	3
Live birth rate/patient	16.6%	44.4%	33.3%	13.3%	10.0%	12.0%

Data are expressed as medians interquartile range (25th percentile–75th percentile)

COS controlled ovarian stimulation, IVM in vitro maturation, FP fertility preservation, OO-COS oocytes cryopreserved after COS, OO-IVM oocytes cryopreserved after IVM, ZYG-COS zygotes cryopreserved after COS, ZYG-IVM zygotes cryopreserved after IVM, no. number of

*Fertilization rate: number of oocytes successfully fertilized divided by the number of mature oocytes

**Implantation rate: number of gestational sacs with a fetal heartbeat divided by the number of embryos transferred