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. 2021 Jul 30;4:929. doi: 10.1038/s42003-021-02446-x

Fig. 6. GLP-grade LmCen/ immunization confers long-term protection against fatal L. donovani infection in hamsters.

Fig. 6

a Schematic representation of experimental plan to determine the long-term protective efficacy of LmCen/ parasites against L. donovani infection through needle injection. b, c Spleen (b) and liver (c) parasite burden of GLP-grade LmCen/ immunized (Imm Chal, n = 6) and age-matched nonimmunized (Non-Imm Chal, n = 5) hamsters were determined at 8 months post-needle challenge. Results (means ± SD) are from one experiment (p values were determined by Mann–Whitney two-tailed test). MPI Months post immunization, MPC months post challenge.