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. 2021 Jul 30;4:929. doi: 10.1038/s42003-021-02446-x

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

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Fig. 7 — a Schematic representation of experiment plan to determine immune response of LmCen^−/− in human PBMCs. b–d Scatter dot plots showing the levels (pg/ml) of pro-inflammatory (IFN-γ) (b) and anti-inflammatory (IL-10) (c) cytokine as well as IFN-γ/IL-10 ratio (d) in culture supernatant of PBMCs from Non-endemic region after 48 h of infection with LmCen^−/− parasites by ELISA. Control group was left uninfected. Results (Mean ± SD) are representative of one experiment (p values were determined by Mann–Whitney two-tailed t test).