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. 2021 Jul 30;12:4645. doi: 10.1038/s41467-021-24910-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Cell proliferation curves of PC3 and Huh7 cells upon siRNA-mediated knockdown of the cscRNAs. The y-axis shows the cell confluence fold-change in relative to the confluence at time 0. The error bars represent the ±SD of three biological replicates. ****p = 0.0001 from two-sided t-test. Source data are provided as a Source data file. b Wound-healing assays showing the cell migration rates of PC3 and Huh7 upon siRNA-mediated knockdown of the cscRNAs. The y-axis shows the wound width at different time points in relative to the wound width at time 0. The error bars represent the ±SD of three biological replicates. ****p = 0.0001 from two-sided t-test. The representative images of the wounds are shown in Fig. S10. Source data are provided as a Source data file. c Formation of PC3 and Huh7 cell colonies upon siRNA-mediated knockdown of the cscRNAs.