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. 2021 Jul 30;11:15545. doi: 10.1038/s41598-021-94820-2

Table 3.

Fold-changes in expression levels of the core biosynthetic genes of secondary metabolite gene clusters of strain S02 compared to strain S25 when F. verticillioides was absent.

ID Type Most similar known cluster (similarity) Paenibacillus sp. S02
Gene ID Fold-change
C1 Nrps Fusaricidin B (100%) KAI36_00078 486.58*
KAI36_00083 20.36*
C2 Siderophore KAI36_00955 11.71*
KAI36_00956 13.93*
KAI36_00959 4.64*
C3 Bacteriocin KAI36_01103 46.95*
C4 Nrps transAT-PKS KAI36_01166 18.88*
KAI36_01170 2.43*
KAI36_01172 1.93*
KAI36_01173 3.31*
KAI36_01175 2.35*
KAI36_01176 2.30*
KAI36_01178 2.27*
KAI36_01179 1.92*
KAI36_01180 – 1.25
KAI36_01181 1.27
C5 Lassopeptide Paeninodin (40%) KAI36_01236 134.38*
KAI36_01240 37.82*
C6 Nrps Marthiapeptide A (33%) KAI36_01339 239.45*
KAI36_01340 159.93*
KAI36_01341 119.29*
C7 Lanthipeptide Paenilan (100%) KAI36_01558 60.94*
KAI36_01560 271.12*
KAI36_01562 69.08*
C9 Nrps-like KAI36_01944 – 7.42*
C10 Nrps Tridecaptin (100%) KAI36_02333 7.74*
KAI36_02334 32.36*
C11 Nrps transAT-PKS Paenilipoheptin (S02, 73%; S25, 76%) KAI36_02506 17.20*
KAI36_02507 29.10*
KAI36_02508 23.54*
KAI36_02509 22.65*
KAI36_02510 10.63*
C14 Nrps T3PKS transAT-PKS Aurantinin B/C/D (35%) KAI36_03362 118.38*
KAI36_03363 46.83*
KAI36_03365 125.65*
KAI36_03366 98.69*
KAI36_03367 31.92*
KAI36_03368 77.19*
KAI36_03371 134.46*
KAI36_03372 113.90*
C15 Nrps Polymyxin (100%) KAI36_04684 9.61*
KAI36_04687 8.61*
KAI36_04688 9.86*
C16 Phosphonate KAI36_05277 15.10*

Clusters in bold: Known antimicrobial compounds.

*Genes that were differentially expressed (q-value < 0.05 and absolute fold-change ≥ 1.5) when comparing the two strains.