Table 2.
Number of participants reporting local and systemic solicited AEs.
| ChAdOx1 Chik 5 × 109 vp (n = 6) | ChAdOx1 Chik 2.5 × 1010 vp (n = 9) | ChAdOx1 Chik 5 × 1010 vp (n = 9) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Any | Mild | Moderate | Severe | Any | Mild | Moderate | Severe | Any | Mild | Moderate | Severe | |
| Any symptom | 4 (67%) | 4 (67%) | 0 | 0 | 9 (100%) | 6 (67%) | 3 (33%) | 0 | 9 (100%) | 4 (44%) | 3 (33%) | 2 (22%) |
| Any local symptom | 3 (50%) | 3 (50%) | 0 | 0 | 9 (100%) | 8 (89%) | 1 (11%) | 0 | 7 (78%) | 5 (56%) | 2 (22%) | 0 |
| Pain | 3 (50%) | 3 (50%) | 0 | 0 | 9 (100%) | 8 (89%) | 1 (11%) | 0 | 7 (78%) | 5 (56%) | 2 (22%) | 0 |
| Pruritus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Warmth | 0 | 0 | 0 | 0 | 4 (44%) | 4 (44%) | 0 | 0 | 3 (33%) | 3 (33%) | 0 | 0 |
| Swelling | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Erythema | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (11%) | 1 (11%) | 0 | 0 |
| Any systemic symptom | 2 (33%) | 2 (33%) | 0 | 0 | 9 (100%) | 6 (67%) | 3 (33%) | 0 | 9 (100%) | 4 (44%) | 3 (33%) | 2 (22%) |
| Fever | 0 | 0 | 0 | 0 | 2 (22%) | 2 (22%) | 0 | 0 | 2 (22%) | 2 (22%) | 0 | 0 |
| Feverishness | 1 (17%) | 1 (17%) | 0 | 0 | 6 (67%) | 3 (33%) | 3 (33%) | 0 | 7 (78%) | 4 (44%) | 2 (22%) | 1 (11%) |
| Arthralgia | 0 | 0 | 0 | 0 | 3 (33%) | 3 (33%) | 0 | 0 | 4 (44%) | 0 | 3 (33%) | 1 (11%) |
| Myalgia | 1 (17%) | 1 (17%) | 0 | 0 | 7 (78%) | 6 (67%) | 1 (11%) | 0 | 6 (67%) | 2 (22%) | 3 (33%) | 1 (11%) |
| Headache | 1 (17%) | 1 (17%) | 0 | 0 | 7 (78%) | 6 (67%) | 1 (11%) | 0 | 6 (67%) | 3 (33%) | 1 (11%) | 2 (22%) |
| Fatigue | 2 (33%) | 2 (33%) | 0 | 0 | 5 (56%) | 5 (56%) | 0 | 0 | 8 (89%) | 4 (44%) | 4 (44%) | 0 |
| Nausea | 0 | 0 | 0 | 0 | 2 (22%) | 1 (11%) | 1 (11%) | 0 | 3 (33%) | 1 (11%) | 2 (22%) | 0 |
| Malaise | 1 (17%) | 1 (17%) | 0 | 0 | 6 (67%) | 6 (67%) | 0 | 0 | 5 (56%) | 1 (11%) | 3 (33%) | 1 (11%) |