Table 2.
Effect of nanocarrier drug compare to free drug on bacterial susceptibility (mean count ± SD) in broth dilution method.
| Name | Bacterial count (CFU/ml) at 0 h | Bacterial count (CFU/ml) at 6 h | Bacterial count (CFU/ml) at 12 h |
|---|---|---|---|
| C1 | 3.67 ± 0.47 × 106 | 2.33 ± 0.47 × 104 | 2.5 ± 0.82 × 105 |
| C2 | 3.67 ± 0.47 × 106 | TFTC | TFTC |
| C3 | 3.67 ± 0.47 × 106 | TFTC | TFTC |
| C4 | 3.67 ± 0.47 × 106 | TFTC | TFTC |
| D1 | 3.67 ± 0.47 × 106 | 1.67 ± 0.47 × 106 | 1.90 ± 0.82 × 106 |
| D2 | 3.67 ± 0.47 × 106 | 1.17 ± 0.12 × 106 | 2.4 ± 0.82 × 106 |
| D3 | 3.67 ± 0.47 × 106 | 5.50 ± 0.50 × 105 | 7.50 ± 0.50 × 105 |
| D4 | 3.67 ± 0.47 × 106 | TFTC | TFTC |
| Nanocarrier | 3.67 ± 0.47 × 106 | 6.67 ± 0.94 × 105 | 3.67 ± 0.47 × 105 |
| Control | 3.67 ± 0.47 × 106 | TNTC | TNTC |
TNTC too numerous to count, TFTC too few to count, C1, C2, C3, C4 nano carrier with 1, 5, 10, and 20 µg/ml CFX respectively, D1, D2, D3, D4 1, 5, 10, and 20 µg/ml CFX, respectively.