Table 3.
Brain-plasma ratio of LLNL-02 (1) at Tmax following a single IV dose of 14C-LLNL-02 to male guinea pigs.
| LLNL-02 dose (mg/kg) | Brain/plasma | logBB |
|---|---|---|
| 1 | 0.132 | − 0.879 |
| 5 | 0.224 | − 0.650 |
| 10 | 0.488 | − 0.311 |
| 20 | 0.529 | − 0.276 |
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