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. 2021 Apr 17;28(8):4334–4341. doi: 10.1016/j.sjbs.2021.04.020

Table 2.

Analgesic activity of C. maxima and C. sativus seeds extract by Tail flick method.

Groups & Doses mg/Kg Reaction time (Sec)
0 h 1 h 2 h 3 h 4 h
Control 1.79 ± 0.15 1.91 ± 0.20 2.76 ± 0.51 2.210 ± 0.26 1.58 ± 0.17
C. maxima 50 1.67 ± 0.12 4.65 ± 0.17** 4.13 ± 0.31** 3.58 ± 0.26** 3.46 ± 0.20**
C. maxima 100 1.76 ± 0.09 4.88 ± 0.25** 3.42 ± 0.25* 3.63 ± 0.35** 3.56 ± 0.28**
C. maxima 200 1.60 ± 0.08 3.68 ± 0.34** 4.10 ± 0.32** 3.03 ± 0.13* 2.93 ± 0.23*
C. sativus 50 1.21 ± 0.07 3.51 ± 0.3 3.27 ± 0.27 2.86 ± 0.40 2.71 ± 0.23
C. sativus 100 1.70 ± 0.16 3.94 ± 0.19** 3.79 ± 0.30* 3.60 ± 0.33** 2.63 ± 0.28
C. sativus 200 1.71 ± 0.12 4.36 ± 0.27** 3.52 ± 0.29* 3.37 ± 0.29** 2.34 ± 0.25
Aspirin 300 1.60 + 0.14 5.23 + 0.57** 4.16 + 0.43** 3.91 + 0.38** 3.75 + 0.35**
Brufen 100 1.46 + 0.13 4.97 + 0.25** 4.89 + 0.57** 5.35 + 0.59** 3.70 + 0.21**

n = 10, Mean ± SEM; *P < 0.05 significant; ** P < 0.01 highly significant as compare to control.